Extend the capabilities in Origin by installing free Apps available from our website. Origin graphs and analysis results can automatically update on data or parameter change, allowing you to create templates for repetitive tasks or to perform batch operations from the user interface, without the need for programming. Origin offers an easy-to-use interface for beginners, combined with the ability to perform advanced customization as you become more familiar with the application. Origin is the data analysis and graphing software of choice for over half a million scientists and engineers in commercial industries, academia, and government laboratories worldwide. RS and GIS Data: NetCDF and GeoTIFF Handing and Graphing.Browser Graph for Multichannel Data Exploration.Extended Templates from OriginLab Website.Message: 'Optimization terminated successfully.' Jac : array() Res = op.minimize(phaseDecay, x0, method='SLSQP', constraints=cons,Īnd I get the following: fun : 30.45577816182897 Y = Plateau+SpanFast*np.exp(-KFast*xdata)+SpanSlow*np.exp(-KSlow*xdata)ĭata = np.loadtxt('data_phase_decay.txt') Y0, Plateau, PercentFast, KFast, KSlow = x I did it this way: import scipy.optimize as op You can do it with SciPy if you convert your objective function into a sum of squared differences and then use a method that supports linear inequalities, like SLSQP. Y = Plateau+SpanFast*np.exp(-KFast*x)+SpanSlow*np.exp(-KSlow*x) import scipy.optimize as opĭef phaseDecay(x, Y0, Plateau, PercentFast, KFast, KSlow): But how is this done in python? How can you constraint a parameter based on another parameter KFast>KSlow. And I think it is because I don't have the constraints: KFast>KSlow>0.
When I do the calculations in python using _fit I get a different result than graphpad prism. Y=Plateau + SpanFast * exp(-KFast * X) + SpanSlow * exp(-KSlow * X) SpanSlow=(Y0-Plateau) * (100-PercentFast) *. I am trying to fit a non-linear regression (two phase exponential decay) of the form
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